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Gene Expression Market to Undertake Strapping Growth By 2028

The global gene expression market size is anticipated to reach USD 19.4 billion by 2028 registering a CAGR of 9.96% from 2021 to 2028, according to a new report by Grand View Research, Inc. Rise in investments for the development of alternative drug discovery approaches coupled with an increase in research activities for genetic studies is expected to drive the global market.

A rise in awareness about the potential application of genetic studies has led to an increase in investments for the development and launch of novel products. For instance, in August 2020, Lexogen GmbH launched the QuantSeq-Pool Sample-Barcoded 3’ mRNA-Seq Library Prep Kit to expedite multiplexing capacities during gene expression profiling. The company’s new QuantSeq-Pool kit also facilitates the sequencing of up to 36,864 RNA samples in parallel, thereby reducing cost and time. 

Furthermore, the decrease in cost associated with sequencing posed as a major driver in the last few years. According to the National Human Genome Research Institute (NHGRI), the cost of sequencing per genome reduced from USD 46.77 thousand in 2010 to USD 0.689 thousand in 2020. This dramatic 98.5% decline in sequencing costs within a decade has increased research involving genomic expression profiling studies.

Request a free sample copy or view report summary: Gene Expression Market Report

Gene Expression Market Report Highlights

  • cDNA synthesis & conversion dominated the process segment in 2020. High demand for personalized medicine coupled with technological advancements in sequencing techniques has enhanced the application of cDNA synthesis to produce genomic libraries

  • Moreover, the introduction of systems that provide direct library synthesis has eliminated the need for prior steps, which increases revenue share

  • Kits and reagents product generated the largest revenue in 2020 due to their high usage during the process

  • In addition, ongoing innovation in the kits and reagents dedicated for specific applications contributes to the highest share of the segment

  • High-Plex capacity is expected to register the fastest CAGR during the forecast period owing to the higher accuracy and increased application in cancer research

  • RNA exp. was the largest revenue-contributing technique in 2020 owing to higher adoption of RNA exp. analysis

  • Moreover, the introduction of high-throughput validation methods, such as targeted RNA sequencing, which are useful in broader screening technologies, has increased the revenue generation in the segment

  • The drug discovery & development segment accounted for the largest revenue share in 2020 as Gene Exp. Signature (GES) is commonly used for the development of novel molecules for multifactorial cellular diseases like cancer, diabetes, tuberculosis, malaria, AIDS, and other infectious diseases

  • North America was the dominant regional market in 2020. This can be attributed to the high adoption of advanced gene exp. technology in the region

  • Major market participants, such as Thermo Fisher Scientific, Inc. and Agilent Technologies, have undertaken strategic initiatives to strengthen their position in the market

  • In March 2020, Thermo Fisher Scientific, Inc. launched the PowerTrack SYBR Green PCR Master Mix for real-time PCR workflow. The product is intended to amplify targets for precise analysis

Gene Expression Market Segmentation

Grand View Research has segmented the global gene expression market on the basis of process, product, capacity, technique, application, and region:

Gene Expression Process Outlook (Revenue, USD Million, 2017 - 2028)

  • Sample Collection

  • Purification

  • cDNA Synthesis & Conversion

  • PCR Analysis

  • Data Analysis & Interpretation

Gene Expression Product Outlook (Revenue, USD Million, 2017 - 2028)

  • Kits & Reagents

  • DNA Chip/Microarray

  • Others

Gene Expression Capacity Outlook (Revenue, USD Million, 2017 - 2028)

  • Low- to Mid-Plex

  • High-Plex

Gene Expression Technique Outlook (Revenue, USD Million, 2017 - 2028)

  • RNA Exp.

    • Northern Blotting

    • DNA Microarrays

    • PCR Techniques

    • RNA-Seq

  • Promoter Analysis

    • In vitro Transcription/Nuclear Run-On Assays

    • Gel Shift Assays

    • Chromatin Immunoprecipitation (ChIP) Assays

  • Protein Exp. & Posttranslational Modification Analysis

    • Western Blotting

    • 2-D Gel Electrophoresis

    • Immunoassays

    • Mass Spectrometry

Gene Expression Application Outlook (Revenue, USD Million, 2017 - 2028)

  • Drug Discovery & Development

  • Clinical Diagnostics

    • RNA Exp.

    • Other Techniques

  • Biotechnology & Microbiology

  • Others

Gene Expression Regional Outlook (Revenue, USD Million, 2017 - 2028)

  • North America

    • U.S.

    • Canada

  • Europe

    • Germany

    • France

    • U.K.

    • Italy

    • Spain

  • Asia Pacific

    • Japan

    • China

    • India

    • Australia

    • South Korea

  • Latin America

    • Brazil

    • Mexico

  • Middle East Africa (MEA)

    • South Africa

    • Saudi Arabia

List of Key Players of Gene Expression Market


  • Quest Diagnostics, Inc.

  • F. Hoffmann-La Roche Ltd.

  • Illumina, Inc.

  • PerkinElmer, Inc.

  • Bio-Rad Laboratories

  • Thermo Fisher Scientific, Inc.

  • Agilent Technologies

  • GE Healthcare

  • Promega Corp.

  • Luminex Corp.

  • Takara Bio, Inc.

  • Danaher Corp.

  • ELITechGroup

  • AutoGenomics

  • Biocartis NV

  • IntegraGen

  • Interpace Biosciences, Inc.

  • Fluidigm Corp.

About Grand View Research

Grand View Research, Inc. is a U.S. based market research and consulting company, registered in the State of California and headquartered in San Francisco. The company provides syndicated research reports, customized research reports, and consulting services. To help clients make informed business decisions, we offer market intelligence studies ensuring relevant and fact-based research across a range of industries, from technology to chemicals, materials and healthcare.

on February 25 at 7:11

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