Thousands of illnesses have no known source
More than 15,700 laboratory-confirmed U.S. cases of cyclosporiasis have been reported since May 1, making 2026 an unusually severe year for the parasitic illness.
Health officials have linked 10,930 cases in the largest outbreak to iceberg lettuce from Taylor Farms de Mexico, but thousands of other illnesses are not part of that outbreak.
The CDC and FDA are investigating at least six other clusters, but so far officials have not publicly identified another food responsible for those illnesses.
The massive U.S. Cyclospora outbreak continues to grow, and while health officials have firmly identified iceberg lettuce as the source of the largest group of illnesses, they still haven't solved an important part of the mystery: What's causing thousands of other cases?
As of Aug. 17, the Centers for Disease Control and Prevention (CDC) had received reports of 15,716 laboratory-confirmed cases of cyclosporiasis acquired in the United States since May 1. That's dramatically higher than the 1,180 cases reported during roughly the same period in 2025.
The CDC says at least 11,841 additional illnesses may require further investigation and analysis, meaning the eventual total could rise substantially.
The good news for investigators is that they have made considerable progress in explaining the largest portion of the outbreak.
Lettuce source firmly established
In an update posted Aug. 20, the CDC said 10,930 cases, 454 hospitalizations, and two deaths have now been associated with a multi-state outbreak linked to iceberg lettuce from Taylor Farms de Mexico. Cases have been identified in 17 states.
Investigators used epidemiological and traceback evidence to connect illnesses to processed iceberg lettuce sourced from central Mexico. Some of the lettuce was served at Taco Bell restaurants, although subsequent investigation found exposure at other locations as well.
Taylor Farms recalled all iceberg lettuce sourced from central Mexico on July 17. The products' best-by dates have since passed, and the CDC says the recalled lettuce should no longer be available in stores or restaurants.
That means the continuing increase in reported cases doesn't necessarily indicate contaminated lettuce is still being sold. Cyclospora cases can take weeks to investigate, confirm, and add to the official count.
What about the other cases?
That's where the investigation becomes more complicated.
The CDC says it is investigating at least six other clusters of cyclosporiasis for which a source has not yet been identified, along with illnesses that are unrelated to the Taylor Farms outbreak.
So far, federal health officials have not announced another specific food as the source of those clusters.
That doesn't necessarily mean lettuce is responsible for all of them. Cyclospora has previously been associated with a wide range of fresh produce, including raspberries, basil, cilantro, parsley, broccoli, cabbage, snow peas, sugar snap peas, and other leafy greens.
Investigations can be particularly difficult when people have eaten foods such as salads or salsa containing several types of produce. Identifying which ingredient carried the parasite can require extensive interviews and traceback work.
Cyclospora also presents investigators with another problem. Unlike bacteria such as Salmonella, scientists can't currently use whole-genome sequencing to precisely compare Cyclospora samples. Instead, the CDC uses genetic testing of selected markers to help determine which illnesses may be related.
Symptoms to watch for
Cyclospora is a microscopic parasite that causes cyclosporiasis. Symptoms typically begin about a week after contaminated food or water is consumed, although they can appear anywhere from two days to two weeks or longer.
The most common symptom is frequent watery diarrhea. Other symptoms can include loss of appetite, weight loss, cramping, bloating, nausea, and fatigue. Untreated illness can last weeks and symptoms sometimes disappear before returning.
Consumers with persistent symptoms should contact a healthcare provider and mention the possibility of Cyclospora infection because routine stool testing doesn't always include the parasite.
For now, health officials appear to have solved the biggest piece of the 2026 outbreak by tracing thousands of illnesses to iceberg lettuce. But with six additional clusters still under investigation and thousands of cases outside the main outbreak, the search for other contaminated foods is far from over.
Photo By CNET
Posted: 2026-08-21 12:58:10
















