Medicine News Car T Cell Therapy Reaches Beyond Cancer Penn Medicine

Expanding CAR T-Cell Access With Broader Criteria and Real-World Data: Clark Alsfeld, MD

At the Institute for Value-Based Medicine ® event in New Orleans, Louisiana, on November 4, Clark Alsfeld, MD, a hematology and oncology specialist at Ochsner MD Anderson, spoke about the availability ... Read More

Dual-target CAR T cell therapy shrinks tumors in aggressive brain cancer

A dual-target CAR T cell therapy approach shows promise for slowing tumor growth in a notoriously aggressive and fast-growing brain cancer. Tumors became smaller after the experimental CAR T cell ... Read More

Dual-Target CAR-T Cell Therapy Slows Glioblastoma Tumors in Phase I Trial

Glioblastoma (GBM) is an aggressive and common brain cancer in adults with average life expectancies of 12–18 months after diagnosis and median survival rate for recurrent GBM ranging from 6–10 months ... Read More

Next-generation CAR T cells could expand solid cancer treatment options

Chimeric antigen receptor (CAR) T cell therapy, which uses a patient's own immune cells to fight cancer, has emerged as a powerful way to treat lymphoma and other blood cancers. But researchers have ... Read More

Study reveals why some myeloma patients stay cancer-free for years after CAR T therapy

A new study from the Icahn School of Medicine at Mount Sinai helps explain why some people with multiple myeloma, a type of blood cancer, stay in remission for many years after receiving CAR T cell ... Read More

CAR-T cell therapy is revolutionising cancer treatment – here’s how it works

Recreation of CAR-T cells attacking a cancerous melanoma cell. Nemes Laszlo/Shutterstock Personalised medicine is already a reality in clinical practice, and CAR-T cell therapy is one of its most ... Read More

VIDEO: Differences in CAR-T therapy examined at LLM

In this video, Catherine S. Diefenbach, MD, discusses the differences between three FDA-approved CD19-directed chimeric antigen receptor T-cell therapy products for the treatment of lymphoma. Read More

Engineered CAR T cells show promise against solid tumors

Chimeric antigen receptor (CAR) T cell therapy, which uses a patient's own immune cells to fight cancer, has emerged as a powerful way to treat lymphoma and other blood cancers. But researchers have ... Read More

CAR T-Cell Therapy Boosts PFS in Advanced Gastric Cancer

In patients with advanced Claudin-18 isoform 2 (CLDN18.2) -positive gastric or gastroesophageal junction cancers, satricabtagene autoleucel (satri-cel) chimeric antigen receptor (CAR) T-cell therapy ... Read More

Penn Medicine, CHOP to begin testing specialized gene therapy after working on new FDA protocol

Penn and CHOP researchers will utilize the new protocol to distribute customizable drugs that target specific genetic disorders. Read More