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Targeted therapies, such as trastuzumab and imatinib, have revolutionized the treatment of cancer patients. All such drugs used thus far in the clinic target oncogenes rather than tumor suppressor genes. This is because drugs generally inhibit the action of proteins, and oncogenic proteins are activated by mutations or amplifications. By contrast, the proteins encoded by…
Source:science.sciencemag.org
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Source:science.sciencemag.org
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Francis Collins By Jocelyn KaiserMar. 1, 2021 , 4:00 PM Responding to concerns about discrimination against Black people, National Institutes of Health (NIH) Director Francis Collins today issued an unusual public apology for what he called “structural racism in biomedical research” and pledged to address it with a sweeping set of actions.
Source:www.sciencemag.org
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Source:www.sciencemag.org
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T cells attacking tumor cells By Jocelyn KaiserMar. 1, 2021 , 11:00 AM Researchers have shown in mice that designer antibodies can curb the growth of tumors by targeting two of cancer’s most infamous offenders—the proteins RAS and p53, which are mutated in many tumors but have largely defied drug development efforts. If their promise…
Source:www.sciencemag.org
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Source:www.sciencemag.org
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One evening Adam Mastroianni was reluctantly putting on his bow tie for yet another black-tie party at the University of Oxford that he had no interest in attending. Inevitably, Mastroianni, then a master’s student in psychology at the university, knew that he would wind up stuck in some endless conversation that he did not want…
Source:www.scientificamerican.com
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Source:www.scientificamerican.com
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IMAGE: The 2022 Vilcek Prizes for Creative Promise in Biomedical Science view more Credit: The Vilcek Foundation NEW YORK, March 1, 2021--The Vilcek Foundation has announced that in 2022 it will award three Vilcek Prizes for Creative Promise in Biomedical Science. The foundation has allocated $150,000 to make three awards of $50,000 each to early-career biomedical…
Source:www.eurekalert.org
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Source:www.eurekalert.org
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hakule/iStock By Jeffrey BrainardMar. 1, 2021 , 10:45 AM For many busy working scientists, receiving yet another invitation from an academic journal to peer review yet another manuscript can trigger groans. The work is time-consuming, and rewards can seem intangible. What’s more, the reviewers work for free, even as the large commercial publishers that operate…
Source:www.sciencemag.org
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Source:www.sciencemag.org
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