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Science News: Human-on-a-chip model tests cancer drug efficacy and toxicity for therapeutic index

by Hesperos, Inc. A reconfigurable "body-on-a-chip" model could transform drug development by simultaneously measuring compound efficacy and toxicity, for both target cells and other organs, such as the heart and liver. These findings, published in Science Translational Medicine, demonstrate the ability of a body-on-a-chip model to truly revolutionize biomedical research and personalized medicine through more…


Source:medicalxpress.com


Posted: 2019-06-19 11:04:00

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Science News: Human-on-a-chip model tests cancer drug efficacy and toxicity for therapeutic index | Science Daily Reports | RobinsPost News Network - Newscast

Body-on-a-chip Model Tests Efficacy and Toxicity of Cancer Drugs

Thu, 20 Jun 2019 10:17:00 GMT

The therapeutic index measures relative safety of a drug and the range in which a drug dose is determined to have a therapeutic effect before significant toxicity begins to occur. The initial ...

Multi-Organ Lab-on-a-Chip for Cancer Drug Testing

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The device includes human organ-derived tissue constructs that allow for the efficacy ... toxicity. “This is a game changer in the preclinical drug development process, which normally requires an ...

Human-on-a-chip model tests cancer drug efficacy and toxicity for therapeutic index

Wed, 19 Jun 2019 11:02:00 GMT

A reconfigurable "body-on-a-chip" model could transform drug development by simultaneously measuring compound efficacy and toxicity, for both target cells and other organs, such as the heart and liver ...

Human-on-a-chip Model Enables Simultaneous Testing of Cancer Drug Efficacy and Off-Target Toxicity to Enable Determination of Therapeutic Index

Tue, 18 Jun 2019 17:00:00 GMT

In vitro multi-organ system by Hesperos, Inc. realistically replicates the responses of cancer treatments and has potential to inform treatment decisions A reconfigurable “body-on-a-chip” model could ...

Therapeutic Drug Monitoring Market 2019: In-Depth Analysis of Production Demand and Consumption Growth Ratio by 2028

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For selected drugs therapeutic drug monitoring aims to enhance drug efficacy, reduce toxicity or assist with diagnosis. Drug concentration at the site of action cannot be routinely measured, but the ...

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